Cost of living in South San Francisco, CA

South San Francisco is a Census city in San Mateo County, CA. ACS 2024 5-year population is 64,305. Median gross rent is $2,802 (ACS 2024 5-year, this place). Median home value is $1,188,800. Median household income is $136,578. Insurance is the NAIC state average; food is a USDA plan — no town indexes.